2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid has been researched along with ro 46-2005 in 1 studies
| Studies (2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid) | Trials (2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid) | Recent Studies (post-2010) (2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid) | Studies (ro 46-2005) | Trials (ro 46-2005) | Recent Studies (post-2010) (ro 46-2005) |
|---|---|---|---|---|---|
| 7 | 0 | 1 | 26 | 0 | 1 |
| Protein | Taxonomy | 2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid (IC50) | ro 46-2005 (IC50) |
|---|---|---|---|
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | 1 | |
| Endothelin receptor type B | Homo sapiens (human) | 1.1 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.22 | |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | 0.23 | |
| Endothelin-1 receptor | Sus scrofa (pig) | 0.16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Böhm, HJ; Kling, A; Klinge, D; Müller, S; Raschack, M; Riechers, H; Unger, L; Walker, N; Wernet, W | 1 |
1 other study(ies) available for 2-[(4,6-dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid and ro 46-2005
| Article | Year |
|---|---|
Discovery and optimization of a novel class of orally active nonpeptidic endothelin-A receptor antagonists.
Topics: Administration, Oral; Animals; Dansyl Compounds; Death, Sudden; Drug Design; Endothelin Receptor Antagonists; Endothelins; Humans; Ligands; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Receptor, Endothelin A; Receptors, Endothelin; Structure-Activity Relationship; Sulfonamides | 1996 |